PROCESS FOR THE MANUFACTURE OF BIS(PHOSPHINE OXIDE)-AND BIS(PHOSPHONATE)- COMPOUNDS

摘要

A process for the manufacture of bisphosphine oxide compounds and bisphospho - nates as intermediates for the production of bisphosphine ligands, in which in a single step process a) a phosphine oxide compound is reacted in an organic solvent at -70.degree .C to 20.degree.C with 0.5-3 eq. of a lithium or magnesium amide compound, b) 0.5-3 eq. of oxidatively-acting metal salt or metal salt complex are adde d to the suspension obtained in stage a) in a temperature range of -70.degree.C t o 20.degree.C, with a racemate of a bisphosphine oxide compound being obtained; c) a racemate cleavage is carried out if desired; and d) the bisphosphonates obtained in stage b) or c) are converted into bisphosphine oxides.