发明名称 |
Process for preparing acyclic HCV protease inhibitors |
摘要 |
Disclosed are highly convergent processes for preparing compounds of formula (I), which compounds are potent active agents for the treatment of hepatitis C virus (HCV) infection: The disclosed processes use SNAr-type coupling reactions between peptidic compounds having a hydroxyproline moiety of the following formula: and halogenated or sulfonated bromoquinoline compounds.
|
申请公布号 |
US7514557(B2) |
申请公布日期 |
2009.04.07 |
申请号 |
US20050135533 |
申请日期 |
2005.05.23 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
BUSACCA CARL ALAN;FRUTOS ROGELIO PEREZ;HADDAD NIZAR;KAPADIA SURESH R.;LORENZ JON CHARLES;SAHA ANJAN;SENANAYAKE CHRIS HUGH;WEI XUDONG |
分类号 |
C07D215/38;A61K31/44;A61K31/4709;C07C217/84;C07C225/22;C07D277/56;C07D417/04;C07D417/14;C07K5/08;C07K5/083 |
主分类号 |
C07D215/38 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|