| 摘要 |
The present invention discloses the usage of Poly-3-hydroxybutyrates P(3HB) in preparation of beta-lactam compounds and the method for the preparation of beta-lactam compounds of formula (I) using Poly-3-hydroxybutyrates P(3HB) as followed: wherein: R is R1, R2, R3 are lower linear or branched C1-C4 alkyl. It is convenient to synthesize the said compound of formula (I) with the present method. Compared with the previous ones, the present method has less steps and higher yields. Meanwhile, it also avoids the use of the reagents of the environmental for pollution and high cost, so as to reduce the cost and pollution
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