| 发明名称 |
GENOMIC EDITING IN ZEBRAFISH USING ZINC FINGER NUCLEASES |
| 摘要 |
Disclosed herein are methods and compositions for genomic editing of one or more genes in zebrafish, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
|
| 申请公布号 |
CA2700170(A1) |
申请公布日期 |
2009.04.02 |
| 申请号 |
CA20082700170 |
申请日期 |
2008.09.25 |
| 申请人 |
SANGAMO BIOSCIENCES, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
AMACHER, SHARON;DOYON, YANNICK;MCCAMMON, JASMINE;URNOV, FYODOR |
| 分类号 |
A01K67/027;C07K19/00;C12N5/10;C12N15/55;C12N15/62 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
