发明名称 |
ANTI-NKG2A ANTIBODIES AND USES THEREOF |
摘要 |
Described herein are anti-NKG2A antibodies suitable for human therapy, including humanized versions of murine anti-NKG2A antibody Z270, as well as related methods and materials for producing and using such antibodies. Exemplary complementarity-determining regions (CDRs) sequences and sites for optional amino acid back-substitutions in framework region (FR) and/or CDRs of such antibodies are also described. |
申请公布号 |
EP2038306(A1) |
申请公布日期 |
2009.03.25 |
申请号 |
EP20070786885 |
申请日期 |
2007.06.28 |
申请人 |
NOVO NORDISK A/S |
发明人 |
SPEE, PETRUS JOHANNES LOUIS;PADKAER, SOEREN BERG |
分类号 |
C07K16/28;A61K39/395;A61P31/12;A61P35/00;A61P37/00;C07K16/46 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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