CLEARANCE OF RAS-MEDIATED NEOPLASTIC CELLS FROM MIXED CELLULAR COMPOSITIONS USING REOVIRUS

摘要

Reovirus can be used to selectively remove ras-mediated neoplastic cells fro m a cellular composition. It is of particular interest to purge autographs whi ch may contain neoplastic cells with reovirus before transplanting the autograf ts back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.