发明名称 Ansamycin formulations and methods of use thereof
摘要 Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 ("Hsp90").
申请公布号 US2009069281(A1) 申请公布日期 2009.03.12
申请号 US20080229326 申请日期 2008.08.20
申请人 AUSTAD BRIAN C;GRENIER LOUIS;HOLSON EDWARD B;LEE JOHN J;PAK ROGER H;PORTER JAMES R;WRIGHT JAMES L 发明人 AUSTAD BRIAN C.;GRENIER LOUIS;HOLSON EDWARD B.;LEE JOHN J.;PAK ROGER H.;PORTER JAMES R.;WRIGHT JAMES L.
分类号 A61K31/395;A61P35/00;A61P35/02;C07D225/06 主分类号 A61K31/395
代理机构 代理人
主权项
地址