发明名称 CATIONIC ALPHA-AMINO ACID-CONTAINING BIODEGRADABLE POLYMER GENE TRANSFER COMPOSITIONS
摘要 The invention provides gene transfer compositions using as the gene carrier a biodegradable polymer that contains one or more cationic alpha amino acids, such as arginine or agmatine. The compositions form a tight soluble complex with a poly nucleic acid suitable for transfecting target cells to effect translation of the cargo poly nucleic acid by the target cell. Thus, such compounds are useful both in vitro and in vivo.
申请公布号 US2009068743(A1) 申请公布日期 2009.03.12
申请号 US20080197068 申请日期 2008.08.22
申请人 MEDIVAS, LLC 发明人 TURNELL WILLIAM G.;CRUZ-ARANDA GINA ANN;WU MARK MINZHI;CHANTUNG RONALD LEE;GOMURASHVILI ZAZA D.;DEFIFE KRISTIN M.
分类号 C12N15/11;C12N15/87 主分类号 C12N15/11
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