The present invention provides methods for predicting the viability of an embryo or for predicting the likelihood of a negative outcome during pregnancy by identifying the presence or absence of or determining the amount of one or more pregnancy associated markers such as molecular isoforms of hCG in a sample. In many instances, the invention is applicable to embryos generated by in vitro fertilization techniques, for instance, to embryos developing in a growth media. The present invention further provides methods for determining the amount of a pregnancy associated markers such as molecular isoforms of hCG (hCG) in a sample. The present invention also provides a diagnostic kit for predicting the viability of an embryo or for predicting the likelihood of a negative outcome during pregnancy by identifying the presence of or determining the amount of one or more pregnancy associated markers such as molecular isoforms of hCG in a sample.
申请公布号
WO2009032288(A1)
申请公布日期
2009.03.12
申请号
WO2008US10387
申请日期
2008.09.05
申请人
NEW YORK UNIVERSITY SCHOOL OF MEDICINE;PEVSNER, PAUL, H.;NAFTOLIN, FREDERICK;GRIFO, JAMIE;LICCIARDI, FRED
发明人
PEVSNER, PAUL, H.;NAFTOLIN, FREDERICK;GRIFO, JAMIE;LICCIARDI, FRED