发明名称 |
Method for producing and cleaving a fusion proteins with an n-terminal chymosin pro-peptide |
摘要 |
An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polypeptide released under the appropriate conditions.
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申请公布号 |
US7501265(B1) |
申请公布日期 |
2009.03.10 |
申请号 |
US19980402488 |
申请日期 |
1998.04.23 |
申请人 |
SEMBIOSYS GENETICS INC. |
发明人 |
MOLONEY MAURICE;ALCANTARA JOENEL;VAN ROOIJEN GIJS |
分类号 |
C12N15/09;C12P21/04;A23L1/305;A61K38/27;A61K38/55;A61P3/02;A61P43/00;C07K14/61;C07K14/815;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/50;C12N15/62;C12P21/00;C12P21/02;C12P21/06 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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