PHARMACEUTICAL COMPOSITION COMBINING A NON-STEROIDAL ANTI-INFLAMMATORY, A CENTRALLY ACTING MUSCLE RELAXANT AND AN INTERLEUKIN-1 INHIBITOR, WHICH CAN BE USED IN THE TREATMENT OF RHEUMATOID ARTHRITIS AND RELATED DISEASES.

摘要

The invention relates to a pharmaceutical composition comprising the synergic combination of a non-steroidal anti-inflammatory known as acemetacin, a centrally acting muscle relaxant known as methocarbamol and a selective inhibitor of interleukin-1 known as diacerein, as well as pharmaceutically acceptable excipients, which are formulated in a single dosage unit to be administered orally. The composition, which is used to control and treat rheumatoid arthritis and related diseases, provides faster pharmacological action and maximal therapeutic effect in less time, as well as reducing inflammation and pain and altering the course of the disease, thereby reducing the risk of side effects.