COMPOSITION AND METHOD FOR TREATMENT OF AUTOIMMUNE DISEASE
摘要
The present invention provides compositions and methods for the treatment of autoimmune diseases, in particular rheumatoid arthritis. Compounds which function as antagonists of Toll-like Receptor 2 are shown to suppress the immune response which result in the onset and progression of autoimmune disease. In particular monoclonal antibodies which have a binding specificity to Toll-like receptor 2 are disclosed for use in methods for the treatment and/or prophylaxis of autoimmune disease.
申请公布号
WO2009000929(A3)
申请公布日期
2009.02.26
申请号
WO2008EP58339
申请日期
2008.06.27
申请人
OPSONA THERAPEUTICS LIMITED;HEFFERNAN, MARK;O'NEILL, LUKE;MCGUIRK, PETER;KEOGH, BRIAN;LOCHER, CHRISTOPHER
发明人
HEFFERNAN, MARK;O'NEILL, LUKE;MCGUIRK, PETER;KEOGH, BRIAN;LOCHER, CHRISTOPHER