The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as well as their use and method of treatment of cardiovascular events and renal insufficiency.
申请公布号
CA2696689(A1)
申请公布日期
2009.02.26
申请号
CA20082696689
申请日期
2008.08.18
申请人
MERCK FROSST CANADA LTD.
发明人
JUTEAU, HELENE;GALLANT, MICHEL;DUBE, DANIEL;ROY, PATRICK;ASPIOTIS, RENEE;FORTIN, REJEAN;LACOMBE, PATRICK;MCKAY, DANIEL J.;WU, TOM YAO-HSIANG