摘要 |
<p>Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the delta-opioid receptor and may be useful, inter alia , for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other delta-opioid receptor-mediated diseases, disorders, and/or conditions.</p> |