| 发明名称 |
(R)-N-Stereoisomers of 7,8-Saturated-4,5-Epoxy-Morphinanium Analogs |
| 摘要 |
Novel (R)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs are disclosed. Pharmaceutical compositions containing the (R)-N-stereoisomers of 7,8-saturated-4,5-epoxy-morphinanium analogs and methods for their pharmaceutical uses are also disclosed. Such analogs are disclosed as being useful in treating, among varying conditions, opioid-induced constipation.
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| 申请公布号 |
US2009047279(A1) |
申请公布日期 |
2009.02.19 |
| 申请号 |
US20070944389 |
申请日期 |
2007.11.21 |
| 申请人 |
PROGENICS PHARMACEUTICALS, INC. |
发明人 |
PEREZ JULIO;HAN AMY QI;ROTSHTEYN YAKOV |
| 分类号 |
A61K39/395;A61K31/439;A61K36/00;A61P1/00;A61P1/10;C07D491/08 |
主分类号 |
A61K39/395 |
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