发明名称 |
Pharmaceutical composition for obstructive vascular disease |
摘要 |
Provided is the excellent prevention or treatment of a vascular occlusive disease such as vascular restenosis. A pharmaceutical composition for a obstructive vascular disease comprising a nucleic acid construct capable of inhibiting the expression of a midkine gene through RNA interference and a collagen molecule. The use of the nucleic acid construct capable of inhibiting the expression of an MK protein through RNA interference in the presence of the collagen molecule can provide an excellent inhibitory effect on the thickened vascular intima.
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申请公布号 |
US2009047319(A1) |
申请公布日期 |
2009.02.19 |
申请号 |
US20060921020 |
申请日期 |
2006.05.24 |
申请人 |
KADOMATSU KENJI;BANNO HIROSHI;TAKEI YOSHIFUMI;KOMORI KIMIHIRO;MURAMATSU TAKASHI;SAKUMA SADATOSHI |
发明人 |
KADOMATSU KENJI;BANNO HIROSHI;TAKEI YOSHIFUMI;KOMORI KIMIHIRO;MURAMATSU TAKASHI;SAKUMA SADATOSHI |
分类号 |
A61K31/7105;A61F2/82;A61P9/00 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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