| 发明名称 |
Sulfonamides having antiangiogenic and anticancer activity |
| 摘要 |
Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.
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| 申请公布号 |
US7491718(B2) |
申请公布日期 |
2009.02.17 |
| 申请号 |
US20030681784 |
申请日期 |
2003.10.08 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
COMESS KENNETH M.;ERICKSON SCOTT A.;HENKIN JACK;KALVIN DOUGLAS M.;KAWAI MEGUMI;KIM KI H.;BAMAUNG NWE Y.;PARK CHANG HOON;SHEPPARD GEORGE S.;VASUDEVAN ANIL;WANG JIEYI;BARNES DAVID M.;FIDANZE STEVE D.;KOLACZKOWSKI LAWRENCE;MANTEI ROBERT A.;PARK DAVID C.;SANDERS WILLIAM J.;TEDROW JASON S.;WANG GARY T. |
| 分类号 |
A61K31/435;A61K31/40;A61K31/415;A61K31/42;A61K31/425;A61K31/4965;A61K31/535;C07C255/03;C07D213/70;C07D231/18;C07D241/04;C07D263/02;C07D265/30;C07D277/02;C07D279/12 |
主分类号 |
A61K31/435 |
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