发明名称 |
Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof |
摘要 |
The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.
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申请公布号 |
US7491489(B2) |
申请公布日期 |
2009.02.17 |
申请号 |
US20050262044 |
申请日期 |
2005.10.28 |
申请人 |
THE UNIVERSITY OF HONG KNOG |
发明人 |
ZHENG BOJIAN;GUAN YI;HUANG JIANDONG;HE MING-LIANG |
分类号 |
C12Q1/00;C12Q1/18;C12Q1/70;G01N33/53 |
主分类号 |
C12Q1/00 |
代理机构 |
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地址 |
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