发明名称 |
Verfahren zur Isolierung von Stammzellen aus ein kissenformiges Gewebe der Zähne |
摘要 |
The invention relates to a method for isolating non-embryonic stem cells from a tissue that is located in immediate vicinity of immature, developing teeth or wisdom teeth. The invention further relates to non-embryonic stem cells derived from said tissue. The method according to the invention utilises a living soft tissue residing underneath the dental papilla 12 in immediate vicinity of the apical side of a developing tooth, which is clearly distinguished from other tooth tissue, such as dental papilla 12 or follicle. The pad-like tissue 16 can only be detected in a defined, specific developmental stage in an early phase of root formation. That is, identifying and separating the pad-like tissue 16 is only possible from the appearance of the bony alveolar fundus to the end of the formation of the root of the tooth. |
申请公布号 |
DE602005012081(D1) |
申请公布日期 |
2009.02.12 |
申请号 |
DE20056012081T |
申请日期 |
2005.07.29 |
申请人 |
RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAET BONN;SIEMONSMEIER, JUERGEN;STIFTUNG CAESAR |
发明人 |
SIEMONSMEIER, JUERGEN DR.DR.;DEGISTIRICI, OEZER DR.;THIE, MICHAEL DR.;GOETZ, WERNER PROF.DR. |
分类号 |
A61K35/32;A61P19/00;C12N5/077 |
主分类号 |
A61K35/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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