发明名称 Pyridopyrimidinone Inhibitors of PIM-1 and/or PIM-3
摘要 Compounds of formula (I), useful for inhibiting PIM-I and/or PIM-3: and pharmaceutically acceptable salts thereof, wherein Y, Z, R1, R3, Q, X and R4 are as defined above. Pharmaceutical compositions and methods of treating diseases and conditions, such as cancer, are also disclosed.
申请公布号 US2009042918(A1) 申请公布日期 2009.02.12
申请号 US20060088474 申请日期 2006.10.05
申请人 EXELIXIS, INC. 发明人 KEARNEY PATRICK;BROWN S. DAVID;KOLTUN ELENA S.
分类号 A61K31/41;A61K31/422;A61K31/4439;A61K31/454;A61K31/506;A61P35/00;C07D257/04;C07D333/38;C07D401/12;C07D409/12;C07D413/12;C07D417/12 主分类号 A61K31/41
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