| 摘要 |
<p>Ortho-bis (4, 41-hydroxyphenyl) methylbenzyl alcohol is produced by reducing the dibenzyl-ether of phenolphthalin acid, or p the ester or the chloride thereof, with a complex metallic hydride in a neutral solvent whereby ortho-bis (4, 41-benzyloxyphenyl) methyl-benzylalcohol is obtained, and then splitting off the two benzyl radicals by the action of hydrogen in the presence of a catalyst such as palladium-on-carbon or Raneynickel. Suitable complex metallic hydrides are: LiAlH4, LiBH4, NaAlH4, NaBH4, Mg(AlH4)2, Ca(BH4)2 and Al(BH4)3. Suitable neutral solvents are:- tetrahydrofuran, the dimethyl ether of ethylene glycol, di-n-butyl ether, and a mixture of di-n-butyl ether and benzene. The di-benzyl ether of phenolphthalin acid required as starting-material for the above method is obtained by boiling an alcohol solution of phenolphthalin acid, containing an alkaline alcoholate, with an excess of benzyl chloride.</p> |
