发明名称 |
GENERATION OF HEAVY-CHAIN ONLY ANTIBODIES IN TRANSGENIC ANIMALS |
摘要 |
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic non-human mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal. |
申请公布号 |
KR20090013748(A) |
申请公布日期 |
2009.02.05 |
申请号 |
KR20087020712 |
申请日期 |
2007.01.25 |
申请人 |
ERASMUS UNIVERSITY MEDICAL CENTRE ROTTERDAM |
发明人 |
GROSVELD FRANKLIN GERARDUS;JANSSENS RICHARD WILHELM |
分类号 |
C07K16/00;C12N15/06;C12N15/85 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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