| 发明名称 |
Modulation of phosphoryl transferase activity of glutamine synthetase |
| 摘要 |
Methods of screening and designing compounds as inhibitors of glutamine synthetase, including adenylylated glutamine synthetase, are provided herein. Compounds and compositions useful for the treatment, prevention, and/or amelioration of bacterial infections, including Mycobacterium tuberculosis, are also provided. |
| 申请公布号 |
GB2451594(A) |
申请公布日期 |
2009.02.04 |
| 申请号 |
GB20080018914 |
申请日期 |
2008.10.15 |
| 申请人 |
CSIR;COLIN PETER KENYON;LYNDON CAREY OLDFIELD;CHRISTIAN WYNAND VAN DER WESTHUYZEN;AMANDA LOUISE ROUSSEAU;CHRISTOPHER JOHN PARKINSON |
发明人 |
COLIN PETER KENYON;CHRISTIAN WYNAND VAN DER WESTHUYZEN;LYNDON CAREY OLDFIELD;AMANDA LOUISE ROUSSEAU;CHRISTOPHER JOHN PARKINSON |
| 分类号 |
C12Q1/48;C07D235/04;C07D239/02;C07D239/04;C07D239/10;C07D239/22;C07D239/48;C07D239/50;C07D241/40;C07D401/12;C07D403/04;C07D471/04;C07D473/34;C07D475/02;C07D487/14;G01N33/573;G06F19/00;G06F19/16 |
主分类号 |
C12Q1/48 |
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