发明名称 [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENYL] -5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, IN DIFFERENT CRYSTALLINE FORMS, PHARMACEUTICAL COMPOSITIONS THEREOF
摘要 The present invention provides novel sulfonylurea salts of a salt of formula (I) and polymorph forms thereof. The compounds in their various forms are effective platelet ADP receptor inhibitors and may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also provides a method for preparing such compounds and forms and for preventing or treating thrombosis and thrombosis related conditions in a mammal comprising the step of administering a therapeutically effective amount of a salt of formula (I) or a pharmaceutically acceptable form thereof.
申请公布号 WO2008137809(A3) 申请公布日期 2009.01.22
申请号 WO2008US62584 申请日期 2008.05.02
申请人 PORTOLA PHARMACEUTICALS, INC.;SHARP, EMMA;QUEGAN, LOUISA, JANE;PANDEY, ANJALI;WANG, JUAN;NIEDER, MATTHEW;HUANG, WOLIN 发明人 SHARP, EMMA;QUEGAN, LOUISA, JANE;PANDEY, ANJALI;WANG, JUAN;NIEDER, MATTHEW;HUANG, WOLIN
分类号 C07D409/12;A61K31/517 主分类号 C07D409/12
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