| 摘要 |
<p>The present invention relates to compounds of general formula (I), wherein: R<sub>1</sub> represents halogen, CN or NO<sub>2</sub>; R<sub>2</sub> represents hydrogen or halogen; n represents 1 or 2; R<sub>3</sub> represents phenyl substituted by one or more halogens or C<sub>1</sub>-C<sub>6</sub> alkyls; or a cyclohexyl; as well as the therapeutically-acceptable salts or solvates thereof. These compounds are useful as protease-activated receptor-1 (par-1) antagonists, particularly in the treatment of thrombosis.</p> |
