发明名称 |
ZUSAMMENSETZUNGEN FÜR DIE LOKALISIERTE THERAPIE DES AUGES, VORZUGSWEISE ENTHALTEND TRIAMCINOLON- ACETONID UND HYALURONSÄURE |
摘要 |
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers. |
申请公布号 |
AT418325(T) |
申请公布日期 |
2009.01.15 |
申请号 |
AT20050705784T |
申请日期 |
2005.01.14 |
申请人 |
ALLERGAN, INC. |
发明人 |
HUGHES, PATRICK;OLEJNIK, OREST;WHITCUP, SCOTT;BURKE, JAMES |
分类号 |
A61K9/10;A61K9/00;A61K9/14;A61K31/00;A61K47/36 |
主分类号 |
A61K9/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|