发明名称 MOLECULES FOR TARGETING COMPOUNDS TO VARIOUS SELECTED ORGANS OR TISSUES
摘要 The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.
申请公布号 CA2942716(A1) 申请公布日期 2009.01.15
申请号 CA20082942716 申请日期 2008.07.14
申请人 BIOMARIN TECHNOLOGIES B.V. 发明人 HEEMSKERK, JOHANNES ANTONIUS;VAN DEUTEKOM, JUDITH C. T.;VAN KUIK-ROMEIJN, PETRA;PLATENBURG, GERARD JOHANNES
分类号 C07K7/06;A61K47/48;A61K49/00;A61P3/00;A61P9/00;A61P21/00;C07H21/00;C07K19/00;C12N15/11 主分类号 C07K7/06
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