The present invention is directed to novel polypeptides and compositions capable of binding to the E6 oncoprotein of human papillomavirus (HPV), and to methods of employing the novel polypeptides and compositions of the invention to treat HPV infection. In one aspect, the invention is directed to expression vectors encoding the polypeptides, which contain an E6-binding domain derived from a fragment of FADD, and to host cells containing the vectors.
申请公布号
WO2008097854(A4)
申请公布日期
2009.01.15
申请号
WO2008US52819
申请日期
2008.02.01
申请人
LOMA LINDA UNIVERSITY;DUERKSEN-HUGHES, PENELOPE, J.;FILIPPOVA, MARIA;TUNGTEAKKHUN, SANDY, S.;NEIDIGH, JONATHAN, W.
发明人
DUERKSEN-HUGHES, PENELOPE, J.;FILIPPOVA, MARIA;TUNGTEAKKHUN, SANDY, S.;NEIDIGH, JONATHAN, W.