发明名称 CD44 splice variants in neurodegenerative diseases.
摘要 There is provided a method of treating or preventing a neurodegenerative disease, which includes administration of a composition that includes a reagent capable of modulating expression of ribonucleic acid (RNA) encoded by a nucleic acid, wherein the nucleic acid is selected from a group that includes a contiguous nucleotide sequence being at least 90% homologous to at least 20 nucleotides of: SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 7, or any combination thereof. There is further provided a method of treating or preventing a neurodegenerative disease, which includes administration of a composition that includes a reagent capable of modulating expression and/or activity of a polypeptide, wherein the sequence of the polypeptide is selected from a group that includes a contiguous amino acid sequence being at least 90% homologous to at least 10 amino acid of: SEQ ID NO: 2, SEQ ID NO: 4, SEQ ID NO: 6, SEQ ID NO: 8, or any combination thereof.
申请公布号 CA2692861(A1) 申请公布日期 2009.01.15
申请号 CA20082692861 申请日期 2008.07.10
申请人 NEURIM PHARMACEUTICALS, 1991, LTD 发明人 PINNER ELHANAN;LAUDON MOSHE;ZISAPEL NAVA
分类号 C12Q1/68 主分类号 C12Q1/68
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