发明名称 N-substituted piperidine derivatives as serotonin receptor agents
摘要 Disclosed herein are compounds of Formula I, or a pharmaceutically acceptable salt, amide, ester, or prodrug thereof. Also disclosed are methods of inhibiting an activity of a monoamine receptor comprising contacting the monoamine receptor or a system containing the monoamine receptor with an effective amount of one or more of the compounds of Formula I. Disclosed are also methods of inhibiting an activation of a monoamine receptor comprising contacting the monoamine receptor or a system containing the monoamine receptor with an effective amount of one or more of the compounds of Formula I. Furthermore, methods of treating psychotic disease using a compound of Formula I are disclosed.
申请公布号 US7476682(B2) 申请公布日期 2009.01.13
申请号 US20060417866 申请日期 2006.05.03
申请人 ACADIA PHARMACEUTICALS, INC. 发明人 ANDERSSON CARL-MAGNUS;SCHLIENGER NATHALIE;FEJZIC ALMA;HANSEN EVA LOUISE;PAWLAS JAN
分类号 A61K31/453;A61K31/4523;A61K31/4525;A61K31/454;A61K31/4545;A61K31/517;A61K31/5377;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P15/08;A61P15/10;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P43/00;C07D211/58;C07D211/62;C07D401/06;C07D405/04;C07D405/06;C07D405/12;C07D405/14;C07D411/06;C07D413/06;C07D417/06;C07D521/00 主分类号 A61K31/453
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