发明名称 |
HYDROGEL-DRIVEN DRUG DOSAGE FORM |
摘要 |
A controlled release dosage form has a coated core with the core comprising a drug-containing composition and a water-swellable composition, each occupying separate regions within the core. The drug-containing composition comprises a low-solubility drug and a drug-entraining agent. The coating around the core is water-permeable, water-insoluble and has at least one delivery port therethrough. A variety of formulations having specific dr ug release profiles are disclosed. |
申请公布号 |
CA2395333(C) |
申请公布日期 |
2009.01.13 |
申请号 |
CA20002395333 |
申请日期 |
2000.12.20 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
CURATOLO, WILLIAM JOHN;FRIESEN, DWAYNE THOMAS;SMITH, KELLY LINCOLN;CHIDLAW, MARK BRIAN;THOMBRE, AVINASH GOVIND;BEYERINCK, RONALD ARTHUR;APPEL, LEAH ELIZABETH |
分类号 |
A61K9/22;A61K9/36;A61K9/00;A61K9/28;A61K31/519;A61K47/36;A61K47/38;A61P15/10 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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