TRIPEPTIDYL AMINOPEPTIDASE

摘要

A tripeptidyl aminopeptidase (TPAP) which is encoded by a DNA construct comprising: i) the DNA sequence shown in SEQ ID No. 1, 2 or 3, or ii) the partial TPAP encoding DNA sequence of DSM 9570, or iii ) a nucleotide sequence which hybridizes to an oligonucleotide probe prepared on the basis of the DNA sequences shown in SEQ ID No. 1, 2 or 3 or on the basis of any of the amino acid sequences shown in SEQ ID Nos. 4-14, and which encodes a TPAP. The TPAP may be obtaine d by recombinant DNA technology. TPAP-deficient production strains may be produced by inactivating or modifying a TPAP- encoding DNA sequence.