发明名称 |
FLUOROPHENYL-SUBSTITUTED ALKENYLCARBOXYLIC ACID GUANIDIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC, AND MEDICAMENT CONTAINING THEM |
摘要 |
Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them compounds of the formula I: wherein the substituents R(1) to R(7) are as defined in the claims, and the pharmaceutically tolerated salts thereof are valuable inhibitors of the cellular sodium/ proton exchanger (Na+/H+ exchanger) . They are therefore outstandingly suitable for the treatment of all diseases attributable to increased Na+/H+ exchange. |
申请公布号 |
CA2177007(C) |
申请公布日期 |
2009.01.06 |
申请号 |
CA19962177007 |
申请日期 |
1996.05.21 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
ALBUS, UDO;LANG, HANS JOCHEN;KLEEMANN, HEINZ-WERNER;WEICHERT, ANDREAS;SCHOLZ, WOLFGANG;SCHWARK, JAN-ROBERT |
分类号 |
A61K31/165;C07C279/22;A61K31/155;A61K31/16;A61P1/16;A61P3/08;A61P9/06;A61P9/08;A61P9/10;A61P13/02;A61P15/00;A61P35/00;A61P43/00;C07C277/08 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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