发明名称 |
Compositions and Methods for Detection of Colorectal Cancer |
摘要 |
We have identified a new variant of ileal bile acid binding protein (IBABP), designated IBABP-L, which is a biomarker for colorectal cancer. The transcript for IBABP-L arises from an alternative start site and includes three exons that are absent in IBABP. IBABP-L also shares part of a fourth exon with IBABP. The protein encoded by IBABP-L contains a deduced 49 residue N-terminal sequence that is not found in the IBABP protein. The present invention provides methods for diagnosing colorectal cancer and other compositions and methods based on this discovery.
|
申请公布号 |
US2009005307(A1) |
申请公布日期 |
2009.01.01 |
申请号 |
US20060992279 |
申请日期 |
2006.09.21 |
申请人 |
BURNHAM INSTITUTE FOR MEDICAL RESEARCH |
发明人 |
SMITH JEFFREY W.;FANG CHANGMING |
分类号 |
A61K38/17;A61P35/00;C07H21/00;C07K16/18;C12N5/10;C12N15/11;C12N15/12;C12N15/79;C12Q1/68;G01N33/574 |
主分类号 |
A61K38/17 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|