COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER

摘要

The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrtoIidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrp>lidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIb) Where U is independently selected from: (I) or (II)