METHODS FOR TREATING ABERRANT CELL PROLIFERATION DISORDERS

摘要

The invention relates in part to methods for inhibiting proliferation of cancer cells and treating one or more cell proliferative conditions using compounds described herein It has been determined that compounds described herein inhibit proliferation of cells involved in conditions associated with aberrant cell proliferation. Such conditions include cancers and inflammation conditions. Preferred therapeutic agents include compounds having the general formulae TA1-1A, TA1-1B and TA4-1A in certain embodiments. The therapeutic agents can result in cell apoptosis and cell necrosis and can specifically target proliferation of cells leading to an aberrant cell proliferation condition over "normal" cells.