发明名称 TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROPYRIDOPYRIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
摘要 <p>The present invention is directed to compounds of the formula I:(wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9>, R<10>, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.</p>
申请公布号 SI1501507(T1) 申请公布日期 2008.12.31
申请号 SI20030031285T 申请日期 2003.04.25
申请人 MERCK & CO., INC.;MERCK SHARP & DOHME LTD. 发明人 JIAO RICHARD;MORRIELLO GREGORI;YANG LIHU;GOBLE STEPHEN D.;MILLS SANDER G.;PASTERNAK ALEXANDER;ZHOU CHANGYOU;BUTORA GABOR;KOTHANDARAMAN SHANKARAN;GUIADEEN DEODIALSINGH;TANG CHENG;MOYES CHRISTOPHER
分类号 A61K31/4375;A61K31/4745;A61P29/00;A61P37/02;C07D471/02;C07D471/04;C07D519/00 主分类号 A61K31/4375
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