| 发明名称 |
6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS |
| 摘要 |
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HTreceptor agonists for the treatment of 5-HTassociated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:where:Ris -C≡C-R, -O-R, -S-R, or –NRR; and other substituents are as defined in the specification. |
| 申请公布号 |
EA011011(B1) |
申请公布日期 |
2008.12.30 |
| 申请号 |
EA20060001546 |
申请日期 |
2005.02.18 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
ALLEN JOHN, GORDON;BRINER KARIN;COHEN MICHAEL, PHILIP;GALKA CHRISTOPHER, STANLEY;HELLMAN SARAH, LYNNE;MARTINEZ-GRAU MARIA, ANGELES;REINHARD MATTHEW, ROBERT;RODRIGUEZ MICHAEL, JOHN;ROTHHAAR ROGER, RYAN;TIDWELL MICHAEL, WADE;VICTOR FRANTZ;WILLIAMS ANDREW, CAERWYN;ZHANG DEYI;BOYD STEVEN, ARMEN;CONWAY RICHARD, GERARD;DEO ARUNDHATI, S.;LEE WAI-MAN;SIEDEM CHRISTOPHER, STEPHEN;SINGH AJAY;MAZANETZ MICHAEL, PHILIP |
| 分类号 |
C07D223/16;A61K31/55;A61P3/04;A61P25/22;A61P25/24;A61P25/30;C07D401/12;C07D403/06;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D413/14;C07D417/06;C07D417/12 |
主分类号 |
C07D223/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
