发明名称 |
Primary rat hepatocyte toxicity modeling |
摘要 |
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
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申请公布号 |
US7469185(B2) |
申请公布日期 |
2008.12.23 |
申请号 |
US20030357507 |
申请日期 |
2003.02.04 |
申请人 |
OCIMUM BIOSOLUTIONS, INC. |
发明人 |
MENDRICK DONNA L.;PORTER MARK W.;JOHNSON KORY R.;HIGGS BRANDON;CASTLE ARTHUR L.;ORR MICHAEL;ELASHOFF MICHAEL R. |
分类号 |
G06F19/00 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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