| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: claimed is improved method of obtaining 4,10beta-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,13alpha-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene of formula (III) , in which R' is protective group of hydroxyl group or acetyl, alkoxyacetyl or alkyl radical by interaction of 4-ecetoxy-2a-benzoyloxy-5beta,20-epoxy-1,13alpha-dihydroxy-9-oxo-7beta-trifluormethylsulfonyloxy-tax-11-ene of formula (II) , in which R' has the same values s in formula (III), with weak base, selected from molecular sieves in sulfolane. ^ EFFECT: simplification of process due to elimination of use of alkali metal azide or halogenide and solvent substitution. ^ 10 cl, 3 tbl, 11 ex |
