| 摘要 |
The present invention pertains, at least in part, to a substituted tetracycline compound of Formula (I): wherein X is CHC(R13VY), CR6 R6, C=CR6 R6, S, NR6, or O; E is NR7dR7ß, OR7f or (CH2)o.iC(=W)WR7s; W is O, S, NR711 or CR75R7*; W is O, S or NR7*; These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms. |
| 申请人 |
PARATEK PHARMACEUTICALS, INC.;ABATO, PAUL;ASSEFA, HAREGEWEIN;BERNIAC, JOEL;BHATIA, BEENA;BOWSER, TODD;GRIER, MARK;HONEYMAN, LAURA;ISMAIL, MOHAMED;KIM, OAK, K.;NELSON, MARK;PAN, JINGWEN;VERMA, ATUL |
发明人 |
ABATO, PAUL;ASSEFA, HAREGEWEIN;BERNIAC, JOEL;BHATIA, BEENA;BOWSER, TODD;GRIER, MARK;HONEYMAN, LAURA;ISMAIL, MOHAMED;KIM, OAK, K.;NELSON, MARK;PAN, JINGWEN;VERMA, ATUL |
