发明名称 |
Sensitizing cells for apoptosis by selectively blocking cytokines |
摘要 |
The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis. <IMAGE> |
申请公布号 |
AU2004210432(B2) |
申请公布日期 |
2008.12.18 |
申请号 |
AU20040210432 |
申请日期 |
2004.02.09 |
申请人 |
GIORGIO STASSI;MATILDE TODARO |
发明人 |
GIORGIO STASSI;MATILDE TODARO |
分类号 |
A61K38/17;A61K38/19;A61K38/20;A61K39/395;A61K45/00;A61K45/06;A61P35/00;A61P37/06 |
主分类号 |
A61K38/17 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|