摘要 |
N-{3-[R1-(phenyl)-C(=X)]-phenyl-lower-alkyl}amines having anti-inflammatory utility are prepared either by reduction of a 3-[R1-(phenyl)-CO]-phenyl-lower-alkanoylamine; by benzoylating a phenyl-lower-alkylamine; by reaction of a 3-lithiophenyl-lower-alkylamine with a R1-(phenyl)-carboxaldehyde, a R1-(phenyl)lower-alkyl ketone or a R1-(phenyl)-carbonitrile or by transformations involving manipulations of a carbonyl or carbinol group. |