发明名称 GLUCOSAMINE DERIVATIVE AND ITS PREPARATION
摘要 NEW MATERIAL:A compound (salt) of formula I [R is <=8C organic acid residue; R<1> is H or acyl; R<2> is H or lower alkyl; R<3>,<4> are H or (OH-substituted) lower alkyl; R<5>,<6> are (esterified or amidated) carboxyl; R<7> is H or aralkyl; D, L are steric configulation of the asymmetric C atoms]. EXAMPLE:2-( 2-Acetamido-6-amino-2, 6-dideoxy-D-glucopyranos-3-O-yl )-D-propionyl-L-alanyl-D-isoglutamine. USE:A phylactic agent, carcinostatic agent, and remedy for cancer, having excellent immuno-enhancing activity. PROCESS:Condensation of a compound II with a compound of formula R<1>-OH gives the compound I.
申请公布号 JPS55115895(A) 申请公布日期 1980.09.06
申请号 JP19790023689 申请日期 1979.02.28
申请人 TAKEDA CHEMICAL INDUSTRIES LTD 发明人 YAMAMURA YUUICHI;HASEGAWA AKIRA;AZUMA ICHIROU;KOBAYASHI SAKAE
分类号 C07K9/00;A61K39/39;C07H15/04;C07K1/113 主分类号 C07K9/00
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