| 摘要 |
A topical anti-inflammatory effect in mammals is obtained with particular B2 agonists. The compositions can be for example in the form of sprays, ointments, creams, gels, lotions, and suppositories, all of which are to be applied to the mammal topically, especially phenetharolamines e.g. zinterol, azazinterol and bitolxerol. Also, N-(3-Indolyl-isopropyl)- and N-(3-indolyl-t-butyl)-2-(4-hydroxy-3- methanesulfonamidophenyl)-2- hydroxyethylamines and their pharmaceutically acceptable salts are antiasthmatic agents as demonstrated by bronchodilation action and inhibition of smooth muscle contraction caused by antigen-induced release of chemical mediators. |
