| 摘要 |
PURPOSE:To obtain an antiallergic agent, particularly antihistaminic agent, consisting essentially of 2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)propan-1-ol or a salt thereof as an active ingredient. CONSTITUTION:An antiallergic agent, containing 0.1-10wt%, preferably 0.2-5wt% 2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)propan-1-ol or a salt thereof as an active ingredient and useful for improving symptoms, preventing and treating various allergic diseases, e.g. human bronchial asthma, allergic rhinitis, urticaria, hay fever, etc. Tatrate of the above-mentioned compound is known to have efficiency for improvement of symptom, e.g. vertigo, headache, depression, anxiety, excitement, etc., caused by sequelae of cerebral hemorrhage. Furthermore, calcium antagonistic action and coronary vasodilator action have been found, but antiallergic action thereof is not known at all.
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