| 摘要 |
PURPOSE: To obtain the subject preparation containing a specific alkyl or alkenylarylether derivative as an antiseborrheic medicine in a dermatologically compatible medicine or cosmetic excipient. CONSTITUTION: This preparation contains 0.0005-0.5wt.% of a compound of the formula [R<1> is a 6-20C saturated alicyclic alkyl, a 6-20C mono- or poly- unsaturated linear, branched or alicyclic alkyl; R<2> is a hydroxyalkyl, a hydroxyalkenyl, COOR<3> , CH2 COOR<3> (R<3> is an alkyl, a hydroxyalkyl, etc.), etc.,] as an antiseborrheic medicine in a medicine or cosmetic excipient. The compound of the formula exhibits an excellent sebum secretion-inhibiting activity, expresses the high sebum secretion-inhibiting and antiseborrheic actions even in a very low employment concentration, and is excellent in compatibility with skins and mucous membranes. The preparation can normalize the secretion of sebaceous glands and recover the appearances of sticky hair, greasy skins, etc.
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