发明名称 COMPOSITION AND TREATMENT WITH BIOLOGICALLY ACTIVE PEPTIDES AND ANTIBIOTIC
摘要 A composition comprising at least one biologically active amphiphilic peptide, said peptide being an ion channel-forming peptide, and an antibiotic selected from the class consiting of bacitracins, aminoglycosides, penicillins, monobactams, hydrophobic antibiotics, 50-S ribosome inhibitors, antibiotics having a large lipid-like lactone rings and derivatives or analogues thereof. The biologically active amphiphilic peptide and the antibiotic may be administered in amounts effective to inhibit growth of a target cell. The biologically active amphiphilic peptide and antibiotic may potentiate each other.
申请公布号 CA2013738(A1) 申请公布日期 1990.10.17
申请号 CA19902013738 申请日期 1990.04.03
申请人 MAGAININ SCIENCES, INC. 发明人 ZASLOFF, MICHAEL;BERKOWITZ, BARRY
分类号 A61K38/00;A61K38/04;A61K38/17;A61P31/04;C07K14/46;(IPC1-7):A61K38/00 主分类号 A61K38/00
代理机构 代理人
主权项
地址