发明名称 Sirna Molecules for the Treatment of Blood Vessels
摘要 The present invention relates to a nucleic acid molecule, a genetic construct, siRNA molecules and a composition which comprises the nucleic acid molecule and/or the genetic construct and/or the siRNA molecules and can be used for inhibition of the expression of endothelial adhesion molecules. The invention also relates to a device, which is coated with the aforementioned molecules, the composition or the construct, or contains them. The present invention further relates to a corresponding use of the nucleic acid molecule, of the genetic construct or of the siRNA molecules and a method of inhibition of the expression of adhesion molecules and a method of vessel grafting, lung transplantation, treatment of lung transplants, and a method of treatment of the open heart within the scope of cardioplegia.
申请公布号 US2008260854(A1) 申请公布日期 2008.10.23
申请号 US20060814213 申请日期 2006.01.19
申请人 WALKER TOBIAS;WENDEL HANS-PETER 发明人 WALKER TOBIAS;WENDEL HANS-PETER
分类号 A61K35/42;A01N1/02;A61F2/06;A61K35/44;C07H21/04;C12N7/00;C12N15/113;C12N15/63 主分类号 A61K35/42
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