<p>The present invention provides a process for the preparation of a silicate and carbonate co-substituted calcium phosphate material. The process comprises the steps of: forming a silicon and optionally carbon-containing calcium phosphate precipitate by an aqueous precipitation method involving preparing an aqueous solution comprising phosphate ions, silicate ions, calcium ions and optionally carbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintained above approximately 1.67; and heating the precipitate in an atmosphere comprising carbon and oxygen to form a silicate and carbonate co-substituted calcium phosphate material. The present invention also provides a synthetic carbonate and silicate co-substituted hydroxyapatite material, as well as a biomedical material.</p>
申请公布号
WO2008125829(A1)
申请公布日期
2008.10.23
申请号
WO2008GB01288
申请日期
2008.04.11
申请人
UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN;GIBSON, IAIN, R.;SKAKLE, JANET, M., S.;HADDEN, DANIEL, J.;BUCKLAND, THOMAS
发明人
GIBSON, IAIN, R.;SKAKLE, JANET, M., S.;HADDEN, DANIEL, J.;BUCKLAND, THOMAS